R. Borzilleri: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors

Kyoung Soon Kim, Songfeng Lu, Lyndon A. Cornelius, Louis J. Lombardo, Robert M. Borzilleri, Gretchen M. Schroeder, Christopher Sheng, George Rovnyak, Donald Crews, Robert J. Schmidt, David K. Williams

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 182 KB

english, 2006

2

Synthesis and SAR of 4-(3-hydroxyphenylamino)pyrrolo[2,1-f][1,2,4]triazine based VEGFR-2 kinase inhibitors

Robert M. Borzilleri, Zhen-wei Cai, Christopher Ellis, Joseph Fargnoli, Aberra Fura, Tracy Gerhardt, Bindu Goyal, John T. Hunt, Steven Mortillo, Ligang Qian, John Tokarski, Viral Vyas, Barri Wautlet,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

3

Synthesis and Biological Activity of Novel Epothilone Aziridines †

Regueiro-Ren, Alicia, Borzilleri, Robert M., Zheng, Xiaoping, Kim, Soong-Hoon, Johnson, James A., Fairchild, Craig R., Lee, Francis Y. F., Long, Byron H., Vite, Gregory D.

Journal:

Organic Letters

Year:

2001

Language:

english

File:

PDF, 84 KB

english, 2001

4

106 Preclinical studies and characterization of BMS-794833, a small molecule inhibitor of Met and VEGFR-2 kinases

J. Fargnoli, B.J. Henley, B.S. Wautlet, R. Borzilleri

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 60 KB

english, 2010

5

β-secretase inhibitors for treatment of Alzheimer's disease

O'Neill, Brian T., Brodney, Michael A., Ambroise, Claude, Borzilleri, Kris, Coffman, Karen, Efremov, Ivan, Hajos-Korcsok, Eva, Helal, Christopher, Kauffman, Gregory, Lanyon, Lorraine, Liston, Dane, Ji

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

6

Imino Ene Reactions in Organic Synthesis

R. M. Borzilleri, S. M. Weinreb

Year:

1995

File:

PDF, 1.07 MB

1995

7

The Need for a Separate Consumer Price Index for Older Persons A Review and New Evidence

Borzilleri, T. C.

Journal:

The Gerontologist

Year:

1978

Language:

english

File:

PDF, 731 KB

english, 1978

8

Surface Cultural Concepts: A Design for the Evaluation of Cultural Material in Textbooks

Guenter G. Pfister and Petra A. Borzilleri

Journal:

Die Unterrichtspraxis / Teaching German

Year:

1977

Language:

english

File:

PDF, 595 KB

english, 1977

9

Decarboxylative Peptide Macrocyclization through Photoredox Catalysis

McCarver, Stefan J., Qiao, Jennifer X., Carpenter, Joseph, Borzilleri, Robert M., Poss, Michael A., Eastgate, Martin D., Miller, Michael, MacMillan, David W. C.

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 1.90 MB

english, 2016

10

Delineating the role of cooperativity in the design of potent PROTACs for BTK

Zorba, Adelajda, Nguyen, Chuong, Xu, Yingrong, Starr, Jeremy, Borzilleri, Kris, Smith, James, Zhu, Hongyao, Farley, Kathleen A., Ding, WeiDong, Schiemer, James, Feng, Xidong, Chang, Jeanne S., Uccello

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.20 MB

english, 2018

11

ChemInform Abstract: Synthesis of (9R,12S)- and (9S,12S)-Cycloisodityrosine and Their N- Methyl Derivatives.

D. L. BOGER, J. ZHOU, R. M. BORZILLERI, S. NUKUI, S. L. CASTLE

Journal:

Year:

1997

File:

PDF, 35 KB

1997

12

ChemInform Abstract: Synthesis of the Vancomycin CD and DE Ring Systems.

D. L. BOGER, R. M. BORZILLERI, S. NUKUI, R. T. BERESIS

Journal:

Year:

1997

File:

PDF, 26 KB

1997

13

ChemInform Abstract: A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products.

Robert M. Borzilleri, et al. et al.

Journal:

Year:

2001

Language:

english

File:

PDF, 33 KB

english, 2001

14

ChemInform Abstract: Synthesis and Biological Activity of Novel Epothilone Aziridines.

Alicia Regueiro-Ren, Robert M. Borzilleri, Xiaoping Zheng, Soong-Hoon Kim, James A. Johnson, Craig R. Fairchild, Francis Y. F. Lee, Byron H. Long, Gregory D. Vite

Journal:

Year:

2001

File:

PDF, 40 KB

2001

15

Eight- and Nine-Membered Hetarenes and Heteroannulenes with One or More Heteroatoms

R. M. Borzilleri

Journal:

Year:

2005

File:

PDF, 8 KB

2005

16

Spontaneous α-N-6-Phosphogluconoylation of a “His Tag” inEscherichia coli:The Cause of Extra Mass of 258 or 178 Da in Fusion Proteins

Kieran F. Geoghegan, Henry B.F. Dixon, Philip J. Rosner, Lise R. Hoth, Anthony J. Lanzetti, Kris A. Borzilleri, Eric S. Marr, Linda H. Pezzullo, LeRoy B. Martin, Peter K. LeMotte, Alexander S. McColl,

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 299 KB

english, 1999

17

A new method for preparation of 3,6-dihydro-2H-1,3-oxazines and explorations of their use in stereoselective synthesis of 1,3-amino alcohol derivatives

John P. Cherkauskas, Andrew M. Klos, Robert M. Borzilleri, Joseph Sisko, Steven M. Weinreb, Masood Parvez

Journal:

Year:

1996

Language:

english

File:

PDF, 919 KB

english, 1996

18

An unusually facile SnAr 14-membered biaryl ether macrocyclization reaction suitable for preparation of the cycloisodityrosine subunit of bouvardin, deoxybouvardin and related agents

Dale L. Boger, Robert M. Borzilleri

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 229 KB

english, 1995

19

Synthesis of appropriately functionalized vancomycin CD and DE ring systems

Dale L. Boger, Robert M. Borzilleri, Seiji Nukui

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 394 KB

english, 1995

20

Synthesis of (9S,12S)-cycloisodityrosine and its unnatural (9R,12S)-diastereomer

Dale L. Boger, Jiacheng Zhou, Robert M. Borzilleri, Seiji Nukui

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 207 KB

english, 1996

21

Synthesis, SAR, and Evaluation of 4-[2,4-Difluoro-5-(cyclopropylcarbamoyl)phenylamino]pyrrolo[2,1-f][1,2,4]triazine-based VEGFR-2 kinase inhibitors

Zhen-wei Cai, Donna Wei, Robert M. Borzilleri, Ligang Qian, Amrita Kamath, Steven Mortillo, Barri Wautlet, Benjamin J. Henley, Robert Jeyaseelan Sr., John Tokarski, John T. Hunt, Rajeev S. Bhide, Jose

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

22

Rearrangements of some furan and banzofuran 1.5,-dienols

David Martin, Julie A. Wurster, Mary J. Boylan, Robert M. Borzilleri, Gregory T. Engel, Edward J. Welsh

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 206 KB

english, 1993

23

Preclinical discovery of ixabepilone, a highly active antineoplastic agent

Francis Y. F. Lee, Robert Borzilleri, Craig R. Fairchild, Amrita Kamath, Richard Smykla, Robert Kramer, Gregory Vite

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 451 KB

english, 2008

24

Total Synthesis of the Unusual Marine Alkaloid (−)-Papuamine Utilizing a Novel Imino Ene Reaction J. Am. Chem. Soc. 1995, 117, 10905−10913

Borzilleri, Robert M., Weinreb, Steven M., Parvez, Masood

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 27 KB

english, 1996

25

Discovery and Optimization of a Novel Spiropyrrolidine Inhibitor of β-Secretase (BACE1) through Fragment-Based Drug Design

Efremov, Ivan V., Vajdos, Felix F., Borzilleri, Kris A., Capetta, Steven, Chen, Hou, Dorff, Peter H., Dutra, Jason K., Goldstein, Steven W., Mansour, Mahmoud, McColl, Alexander, Noell, Stephen, Oborsk

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.34 MB

english, 2012

26

ChemInform Abstract: β-Tosylethylamine: A Useful Reagent for Preparation of N- Protected Amides, Carbamates, and Related Compounds. Application to Synthesis of β-Lactams.

D. DIPIETRO, R. M. BORZILLERI, S. M. WEINREB

Journal:

Year:

1995

File:

PDF, 32 KB

1995

27

ChemInform Abstract: Total Synthesis of Papuamine via a Stereospecific Intramolecular Imino Ene Reaction of an Allenylsilane.

R. M. BORZILLERI, S. M. WEINREB, M. PARVEZ

Journal:

Year:

1995

File:

PDF, 30 KB

1995

28

ChemInform Abstract: Total Synthesis of the Unusual Marine Alkaloid (-)-Papuamine Utilizing a Novel Imino Ene Reaction.

R. M. BORZILLERI, S. M. WEINREB, M. PARVEZ

Journal:

Year:

1996

File:

PDF, 33 KB

1996

29

ChemInform Abstract: A New Method for Preparation of 3,6-Dihydro-2H-1,3-oxazines and Explorations of Their Use in Stereoselective Synthesis of 1,3-Amino Alcohol Derivatives.

J. P. CHERKAUSKAS, A. M. KLOS, R. M. BORZILLERI, J. SISKO, S. M. WEINREB, M. PARVEZ

Journal:

Year:

1996

File:

PDF, 35 KB

1996

30

ChemInform Abstract: Synthesis of (9S,12S)-Cycloisodityrosine and Its Unnatural (9R,12S)- Diastereomer.

D. L. BOGER, J. ZHOU, R. M. BORZILLERI, S. NUKUI

Journal:

Year:

1996

File:

PDF, 31 KB

1996

31

ChemInform Abstract: Synthesis of (R)-(4-Methoxy-3,5-dihydroxyphenyl)glycine Derivatives: The Central Amino Acid of Vancomycin and Related Agents.

D. L. BOGER, R. M. BORZILLERI, S. NUKUI

Journal:

Year:

1996

File:

PDF, 35 KB

1996

32

Compensating for Variations in 1 H− 13 C Scalar Coupling Constants in Isotope-Filtered NMR Experiments

Stuart, Ashley C., Borzilleri, Kris A., Withka, Jane M., Palmer, Arthur G.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

33

Design, Synthesis, and Evaluation of Orally Active 4-(2,4-Difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1- f ][1,2,4]triazines as Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Inhibitors

Borzilleri, Robert M., Zheng, Xiaoping, Qian, Ligang, Ellis, Christopher, Cai, Zhen-wei, Wautlet, Barri S., Mortillo, Steve, Jeyaseelan,, Robert, Kukral, Daniel W., Fura, Aberra, Kamath, Amrita, Vyas,

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 459 KB

english, 2005

34

569 POSTER Preclinical studies and characterization of BMS-777607, a small molecule inhibitor of Met receptor tyrosine kinase

J. Fargnoli, R. Borzilleri

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 64 KB

english, 2008

35

560 POSTER Discovery and preclinical characterization of BMS-777607: a potent, small molecule inhibitor of Met receptor tyrosine kinase

R. Borzilleri, J. Fargnoli

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

36

96 Discovery of BMS-817378: a novel prodrug of the dual Met/VEGFR-2 inhibitor BMS-794833

R. Borzilleri, J. Fargnoli

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 59 KB

english, 2010

37

Discovery of Brivanib Alaninate (( S )-(( R )-1-(4-(4-Fluoro-2-methyl-1 H -indol-5-yloxy)-5-methylpyrrolo[2,1- f ][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), A Novel Prodrug of Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinase Inhibitor (BMS-540215)

Cai, Zhen-wei, Zhang, Yongzheng, Borzilleri, Robert M., Qian, Ligang, Barbosa, Stephanie, Wei, Donna, Zheng, Xiaoping, Wu, Lawrence, Fan, Junying, Shi, Zhongping, Wautlet, Barri S., Mortillo, Steve, J

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 243 KB

english, 2008

38

Total Synthesis of the Unusual Marine Alkaloid (-)-Papuamine Utilizing a Novel Imino Ene Reaction

Borzilleri, Robert M., Weinreb, Steven M., Parvez, Masood

Journal:

Journal of the American Chemical Society

Year:

1995

Language:

english

File:

PDF, 1.17 MB

english, 1995

39

Discovery and Evaluation of N -Cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a Selective and Orally Efficacious Inhibitor of Vascular Endothelial Growth Factor Receptor-2

Borzilleri, Robert M., Bhide, Rajeev S., Barrish, Joel C., D'Arienzo, Celia J., Derbin, George M., Fargnoli, Joseph, Hunt, John T., Jeyaseelan, Robert, Kamath, Amrita, Kukral, Daniel W., Marathe, Puni

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 117 KB

english, 2006

40

Discovery and Preclinical Studies of ( R )-1-(4-(4-Fluoro-2-methyl-1 H -indol-5-yloxy)-5- methylpyrrolo[2,1- f ][1,2,4]triazin-6-yloxy)propan- 2-ol (BMS-540215), an In Vivo Active Potent VEGFR-2 Inhibitor

Bhide, Rajeev S., Cai, Zhen-Wei, Zhang, Yong-Zheng, Qian, Ligang, Wei, Donna, Barbosa, Stephanie, Lombardo, Louis J., Borzilleri, Robert M., Zheng, Xiaoping, Wu, Laurence I., Barrish, Joel C., Kim, So

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 77 KB

english, 2006

41

Discovery of the Pyrrolo[2,1- f ][1,2,4]triazine Nucleus as a New Kinase Inhibitor Template

Hunt, John T., Mitt, Toomas, Borzilleri, Robert, Gullo-Brown, Johnni, Fargnoli, Joseph, Fink, Brian, Han, Wen-Ching, Mortillo, Steven, Vite, Gregory, Wautlet, Barri, Wong, Tai, Yu, Chiang, Zheng, Xiao

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 62 KB

english, 2004

42

A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products

Borzilleri, Robert M., Zheng, Xiaoping, Schmidt, Robert J., Johnson, James A., Kim, Soong-Hoon, DiMarco, John D., Fairchild, Craig R., Gougoutas, Jack Z., Lee, Francis Y. F., Long, Byron H., Vite, Gre

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 108 KB

english, 2000

43

Discovery, SAR, and Pharmacokinetics of a Novel 3-Hydroxyquinolin-2(1 H )-one Series of Potent d -Amino Acid Oxidase (DAAO) Inhibitors †

Duplantier, Allen J., Becker, Stacey L., Bohanon, Michael J., Borzilleri, Kris A., Chrunyk, Boris A., Downs, James T., Hu, Lain-Yen, El-Kattan, Ayman, James, Larry C., Liu, Shenping, Lu, Jiemin, Makla

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 767 KB

english, 2009

44

Total Synthesis of Papuamine via a Stereospecific Intramolecular Imino Ene Reaction of an Allenylsilane

Borzilleri, Robert M., Weinreb, Steven M., Parvez, Masood

Journal:

Journal of the American Chemical Society

Year:

1994

Language:

english

File:

PDF, 221 KB

english, 1994

45

Antibody–drug conjugates: current status and future directions

Perez, Heidi L., Cardarelli, Pina M., Deshpande, Shrikant, Gangwar, Sanjeev, Schroeder, Gretchen M., Vite, Gregory D., Borzilleri, Robert M.

Journal:

Drug Discovery Today

Year:

2014

Language:

english

File:

PDF, 876 KB

english, 2014

46

Design and Synthesis of Truncated EGF-A Peptides that Restore LDL-R Recycling in the Presence of PCSK9 In Vitro

Schroeder, Christina I., Swedberg, Joakim E., Withka, Jane M., Rosengren, K. Johan, Akcan, Muharrem, Clayton, Daniel J., Daly, Norelle L., Cheneval, Olivier, Borzilleri, Kris A., Griffor, Matt, Stock,

Journal:

Chemistry & Biology

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

47

Cyclization of N-Terminal S- Carbamoylmethylcysteine Causing Loss of 17 Da from Peptides and Extra Peaks in Peptide Maps

Geoghegan, Kieran F., Hoth, Lise R., Tan, Douglas H., Borzilleri, Kris A., Withka, Jane M., Boyd, James G.

Journal:

Journal of Proteome Research

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

48

Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

Calabrese, Matthew F., Rajamohan, Francis, Harris, Melissa S., Caspers, Nicole L., Magyar, Rachelle, Withka, Jane M., Wang, Hong, Borzilleri, Kris A., Sahasrabudhe, Parag V., Hoth, Lise R., Geoghegan,

Journal:

Year:

2014

Language:

english

File:

PDF, 3.34 MB

english, 2014

49

Synthesis of (9 R ,12 S )- and (9 S ,12 S )-Cycloisodityrosine and Their N -Methyl Derivatives

Boger, Dale L., Zhou, Jiacheng, Borzilleri, Robert M., Nukui, Seiji, Castle, Steven L.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 1.47 MB

english, 1997

50

[Annual Reports in Medicinal Chemistry] Annual Reports in Medicinal Chemistry Volume 44 Volume 44 || Chapter 15 Case History: Discovery of Ixabepilone (IXEMPRATM), a First-in-Class Epothilone Analog for Treatment of Metastatic Breast Cancer

Borzilleri, Robert M.

Year:

2009

Language:

english

File:

PDF, 655 KB

english, 2009

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски